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Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors.
Patel, Hitisha K; Tao, Nianjun; Lee, Kyung-Min; Huerta, Mariela; Arlt, Heike; Mullarkey, Tara; Troy, Steven; Arteaga, Carlos L; Bihani, Teeru.
Affiliation
  • Patel HK; Radius Health, Inc., 950 Winter St., Waltham, MA, 02451, USA.
  • Tao N; Radius Health, Inc., 950 Winter St., Waltham, MA, 02451, USA.
  • Lee KM; UT Southwestern Simmons Cancer Center, 5323 Harry Hines Blvd., Dallas, TX, 75390, USA.
  • Huerta M; UT Southwestern Simmons Cancer Center, 5323 Harry Hines Blvd., Dallas, TX, 75390, USA.
  • Arlt H; Radius Health, Inc., 950 Winter St., Waltham, MA, 02451, USA.
  • Mullarkey T; Radius Health, Inc., 950 Winter St., Waltham, MA, 02451, USA.
  • Troy S; Radius Health, Inc., 950 Winter St., Waltham, MA, 02451, USA.
  • Arteaga CL; UT Southwestern Simmons Cancer Center, 5323 Harry Hines Blvd., Dallas, TX, 75390, USA.
  • Bihani T; Radius Health, Inc., 950 Winter St., Waltham, MA, 02451, USA. tbihani@gmail.com.
Breast Cancer Res ; 21(1): 146, 2019 12 18.
Article in En | MEDLINE | ID: mdl-31852484
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Full text: 1 Database: MEDLINE Main subject: Tetrahydronaphthalenes / Breast Neoplasms / Receptors, Estrogen / Drug Resistance, Neoplasm / Protein Kinase Inhibitors / Cyclin-Dependent Kinase 4 / Cyclin-Dependent Kinase 6 Limits: Animals / Female / Humans Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Tetrahydronaphthalenes / Breast Neoplasms / Receptors, Estrogen / Drug Resistance, Neoplasm / Protein Kinase Inhibitors / Cyclin-Dependent Kinase 4 / Cyclin-Dependent Kinase 6 Limits: Animals / Female / Humans Language: En Year: 2019 Type: Article