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Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.
Wheeler, Jeanna M; McMillan, Pamela; Strovas, Timothy J; Liachko, Nicole F; Amlie-Wolf, Alexandre; Kow, Rebecca L; Klein, Ronald L; Szot, Patricia; Robinson, Linda; Guthrie, Chris; Saxton, Aleen; Kanaan, Nicholas M; Raskind, Murray; Peskind, Elaine; Trojanowski, John Q; Lee, Virginia M Y; Wang, Li-San; Keene, C Dirk; Bird, Thomas; Schellenberg, Gerard D; Kraemer, Brian.
Affiliation
  • Wheeler JM; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • McMillan P; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Strovas TJ; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Liachko NF; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Amlie-Wolf A; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98104, USA.
  • Kow RL; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Klein RL; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Szot P; Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, WA 98104, USA.
  • Robinson L; Department of Pharmacology, Toxicology and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA.
  • Guthrie C; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Saxton A; Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Kanaan NM; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Raskind M; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Peskind E; Geriatric Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Trojanowski JQ; Department of Translational Sciences and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.
  • Lee VMY; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Wang LS; Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Keene CD; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Bird T; Mental Illness Research Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
  • Schellenberg GD; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Kraemer B; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sci Transl Med ; 11(523)2019 12 18.
Article in En | MEDLINE | ID: mdl-31852801
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Full text: 1 Database: MEDLINE Main subject: Brain / Carrier Proteins / Tau Proteins / Poly(A)-Binding Proteins / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals Language: En Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Brain / Carrier Proteins / Tau Proteins / Poly(A)-Binding Proteins / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals Language: En Year: 2019 Type: Article