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c-Cbl targets PD-1 in immune cells for proteasomal degradation and modulates colorectal tumor growth.
Lyle, Chimera; Richards, Sean; Yasuda, Kei; Napoleon, Marc Arthur; Walker, Joshua; Arinze, Nkiruka; Belghasem, Mostafa; Vellard, Irva; Yin, Wenqing; Ravid, Jonathan D; Zavaro, Elias; Amraei, Razie; Francis, Jean; Phatak, Uma; Rifkin, Ian R; Rahimi, Nader; Chitalia, Vipul C.
Affiliation
  • Lyle C; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Richards S; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Yasuda K; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Napoleon MA; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Walker J; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Arinze N; Department of Surgery, Boston University School of Medicine, Boston, MA, USA.
  • Belghasem M; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Vellard I; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Yin W; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Ravid JD; School of Medicine, Boston University, Boston, MA, USA.
  • Zavaro E; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Amraei R; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Francis J; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Phatak U; Department of Surgery, Boston University School of Medicine, Boston, MA, USA.
  • Rifkin IR; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Rahimi N; Veterans Affairs Boston Healthcare System, Boston, MA, USA.
  • Chitalia VC; Department of Surgery, Boston University School of Medicine, Boston, MA, USA.
Sci Rep ; 9(1): 20257, 2019 12 27.
Article in En | MEDLINE | ID: mdl-31882749
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / CD8-Positive T-Lymphocytes / Ubiquitin-Protein Ligases / Proteasome Endopeptidase Complex / Proto-Oncogene Proteins c-cbl / Programmed Cell Death 1 Receptor Limits: Animals / Humans Language: En Year: 2019 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / CD8-Positive T-Lymphocytes / Ubiquitin-Protein Ligases / Proteasome Endopeptidase Complex / Proto-Oncogene Proteins c-cbl / Programmed Cell Death 1 Receptor Limits: Animals / Humans Language: En Year: 2019 Type: Article