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Photo-induced synthesis of molybdenum oxide quantum dots for surface-enhanced Raman scattering and photothermal therapy.
Yu, Haihong; Zhuang, Zhengfei; Li, Dongling; Guo, Yanxian; Li, Yang; Zhong, Huiqing; Xiong, Honglian; Liu, Zhiming; Guo, Zhouyi.
Affiliation
  • Yu H; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Zhuang Z; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Li D; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Guo Y; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Li Y; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Zhong H; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Xiong H; Department of Physics and Optoelectronic Engineering, Foshan University, Guangdong, P. R. China.
  • Liu Z; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
  • Guo Z; MOE Key Laboratory of Laser Life Science & SATCM Third Grade Laboratory of Chinese Medicine and Photonics Technology, College of Biophotonics, South China Normal University, Guangzhou, Guangdong 510631, P. R. China. liuzm021@126.com ann@scnu.edu.cn.
J Mater Chem B ; 8(5): 1040-1048, 2020 02 07.
Article in En | MEDLINE | ID: mdl-31939980
ABSTRACT
By means of a simple and photo-induced method, four colors of molybdenum oxide quantum dots (MoOx QDs) have been synthesized, using Mo(CO)6 as the structural guiding agent and molybdenum source. The as-prepared MoOx QDs display diverse optical properties due to the different configurations of oxygen vacancies in various nanostructures. Among them, crystalline molybdenum dioxide (MoO2) with a deep blue color shows the most intense localized surface plasmon resonance effect in the near-infrared (NIR) region. The strong NIR absorption endows MoO2 QDs with a high photothermal conversion efficiency of 66.3%, enabling broad prospects as a photo-responsive nanoagent for photothermal therapy of cancer. Moreover, MoO2 QDs can also serve as a novel semiconductor substrate for ultrasensitive surface-enhanced Raman scattering (SERS) analysis of aromatic molecules, amino acids and antibiotics, with SERS performance comparable to that of noble metal-based substrates. The therapeutic applications of MoO2 QDs open up a new avenue for tumor nanomedicine.
Subject(s)

Full text: 1 Database: MEDLINE Main subject: Oxides / Quantum Dots / Photothermal Therapy / Molybdenum Limits: Humans Language: En Year: 2020 Type: Article

Full text: 1 Database: MEDLINE Main subject: Oxides / Quantum Dots / Photothermal Therapy / Molybdenum Limits: Humans Language: En Year: 2020 Type: Article