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A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance.
Chivukula, Raghu R; Montoro, Daniel T; Leung, Hui Min; Yang, Jason; Shamseldin, Hanan E; Taylor, Martin S; Dougherty, Gerard W; Zariwala, Maimoona A; Carson, Johnny; Daniels, M Leigh Anne; Sears, Patrick R; Black, Katharine E; Hariri, Lida P; Almogarri, Ibrahim; Frenkel, Evgeni M; Vinarsky, Vladimir; Omran, Heymut; Knowles, Michael R; Tearney, Guillermo J; Alkuraya, Fowzan S; Sabatini, David M.
Affiliation
  • Chivukula RR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. raghu@wi.mit.edu.
  • Montoro DT; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. raghu@wi.mit.edu.
  • Leung HM; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. raghu@wi.mit.edu.
  • Yang J; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA. raghu@wi.mit.edu.
  • Shamseldin HE; Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. raghu@wi.mit.edu.
  • Taylor MS; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • Dougherty GW; Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, USA.
  • Zariwala MA; Harvard Medical School, Boston, MA, USA.
  • Carson J; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Daniels MLA; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Sears PR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • Black KE; Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Hariri LP; Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
  • Almogarri I; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.
  • Frenkel EM; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Vinarsky V; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.
  • Omran H; Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Knowles MR; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Tearney GJ; Department of General Pediatrics, University Children's Hospital Muenster, Münster, Germany.
  • Alkuraya FS; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sabatini DM; Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Nat Med ; 26(2): 244-251, 2020 02.
Article in En | MEDLINE | ID: mdl-31959991

Full text: 1 Database: MEDLINE Main subject: Mucociliary Clearance / Cystic Fibrosis Transmembrane Conductance Regulator / Ciliopathies / NIMA-Related Kinases Type of study: Prognostic_studies Limits: Adolescent / Adult / Child / Female / Humans Language: En Year: 2020 Type: Article

Full text: 1 Database: MEDLINE Main subject: Mucociliary Clearance / Cystic Fibrosis Transmembrane Conductance Regulator / Ciliopathies / NIMA-Related Kinases Type of study: Prognostic_studies Limits: Adolescent / Adult / Child / Female / Humans Language: En Year: 2020 Type: Article