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RIP1 kinase activity is critical for skin inflammation but not for viral propagation.
Webster, Joshua D; Kwon, Youngsu C; Park, Summer; Zhang, Hua; Corr, Nick; Ljumanovic, Nina; Adedeji, Adeyemi O; Varfolomeev, Eugene; Goncharov, Tatiana; Preston, Jessica; Santagostino, Sara F; Patel, Snahel; Xu, Min; Maher, Jonathan; McKenzie, Brent S; Vucic, Domagoj.
Affiliation
  • Webster JD; Departments of Pathology, Genentech, South San Francisco, California, USA.
  • Kwon YC; Translational Immunology, Genentech, South San Francisco, California, USA.
  • Park S; Translational Immunology, Genentech, South San Francisco, California, USA.
  • Zhang H; Translational Immunology, Genentech, South San Francisco, California, USA.
  • Corr N; Safety Assessment, Genentech, South San Francisco, California, USA.
  • Ljumanovic N; Safety Assessment, Genentech, South San Francisco, California, USA.
  • Adedeji AO; Safety Assessment, Genentech, South San Francisco, California, USA.
  • Varfolomeev E; Early Discovery Biochemistry, Genentech, South San Francisco, California, USA.
  • Goncharov T; Early Discovery Biochemistry, Genentech, South San Francisco, California, USA.
  • Preston J; Departments of Pathology, Genentech, South San Francisco, California, USA.
  • Santagostino SF; Safety Assessment, Genentech, South San Francisco, California, USA.
  • Patel S; Discovery Chemistry, Genentech, South San Francisco, California, USA.
  • Xu M; Translational Immunology, Genentech, South San Francisco, California, USA.
  • Maher J; Safety Assessment, Genentech, South San Francisco, California, USA.
  • McKenzie BS; Translational Immunology, Genentech, South San Francisco, California, USA.
  • Vucic D; Early Discovery Biochemistry, Genentech, South San Francisco, California, USA.
J Leukoc Biol ; 107(6): 941-952, 2020 06.
Article in En | MEDLINE | ID: mdl-31985117
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Full text: 1 Database: MEDLINE Main subject: Skin / Vaccinia / Herpesviridae Infections / Dermatitis / Receptor-Interacting Protein Serine-Threonine Kinases Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Skin / Vaccinia / Herpesviridae Infections / Dermatitis / Receptor-Interacting Protein Serine-Threonine Kinases Language: En Year: 2020 Type: Article