Validation of the Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55 and QOLCE-16) for use by parents of young adults with childhood-onset epilepsy.
Epilepsy Behav
; 104(Pt A): 106904, 2020 03.
Article
in En
| MEDLINE
| ID: mdl-32000098
ABSTRACT
OBJECTIVE:
The objective of the study was to validate the parent-proxy reported Quality of Life in Childhood Epilepsy Questionnaire (QOLCE) in a sample of young adults with a history of childhood-onset epilepsy, allowing for the utilization of a consistent informant (the parent) across the youths' stages of development. The 55-item (QOLCE-55) and 16-item versions (QOLCE-16) were evaluated.METHODS:
Data came from 134 young adults (aged 18.0 to 28.5â¯years) with childhood-onset epilepsy, recruited through community and tertiary care centers across Canada. Confirmatory factor analysis (CFA) was used to assess the higher-order factor structure of the QOLCE. Cronbach's alpha was used to evaluate internal consistency. Convergent validity was assessed by intraclass correlation coefficients (ICC) with the youth self-reported Quality of Life in Epilepsy Questionnaire (QOLIE-31-P).RESULTS:
The higher-order factor structure of the QOLCE-55 and QOLCE-16 demonstrated adequate fit QOLCE-55 comparative fit index (CFI)â¯=â¯0.968, Tucker-Lewis index (TLI)â¯=â¯0.966; and root mean square of approximation (RMSEA)â¯=â¯0.061; QOLCE-16 CFIâ¯=â¯0.966, TFIâ¯=â¯0.959, RMSEAâ¯=â¯0.141. Higher-order factor loadings were strong, ranging from 0.71 to 0.90. Internal consistency was excellent for the total score (αQOLCE-55â¯=â¯0.97; αQOLCE-16â¯=â¯0.93) and good-excellent for each subscale (αâ¯>â¯78). Convergent validity was moderate to good for the total score (ICCâ¯>â¯0.72) and each subscale (ICCâ¯>â¯0.51).SIGNIFICANCE:
These findings provide support for the use of the QOLCE-55 and QOLCE-16 among young adults with a history of childhood-onset epilepsy. Utilizing a consistent measure and informant across the stages of development is essential to reliably evaluate change over time.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Parents
/
Quality of Life
/
Surveys and Questionnaires
/
Epilepsy
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Qualitative_research
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
America do norte
Language:
En
Year:
2020
Type:
Article