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Development of an oral bentonite-based modified-release freeze-dried powder of vactosertib: Pharmacokinetics and anti-colitis activity in rodent models of ulcerative colitis.
Jung, Su Young; Park, Ju-Hwan; Baek, Min-Jun; Kim, Gyu-Ho; Kim, Jaehwan; Zheng, Hong-Mei; Kim, Jae-Min; Kang, Il-Mo; Kim, Dae-Duk; Lee, Jangik I.
Affiliation
  • Jung SY; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 08826 Seoul, Republic of Korea.
  • Park JH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 08826 Seoul, Republic of Korea.
  • Baek MJ; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 08826 Seoul, Republic of Korea.
  • Kim GH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 08826 Seoul, Republic of Korea.
  • Kim J; Korea Institute of Geoscience and Mineral Resources, Daejeon, Republic of Korea.
  • Zheng HM; National Center of Efficacy Evaluation for the Development of Health Products Targeting Digestive Disorders, T2B Infrastructure Center for Digestive Disorders, Incheon, Republic of Korea.
  • Kim JM; National Center of Efficacy Evaluation for the Development of Health Products Targeting Digestive Disorders, T2B Infrastructure Center for Digestive Disorders, Incheon, Republic of Korea.
  • Kang IM; Korea Institute of Geoscience and Mineral Resources, Daejeon, Republic of Korea.
  • Kim DD; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 08826 Seoul, Republic of Korea.
  • Lee JI; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 08826 Seoul, Republic of Korea. Electronic address: jangik.lee@snu.ac.kr.
Int J Pharm ; 578: 119103, 2020 Mar 30.
Article in En | MEDLINE | ID: mdl-32036008
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Full text: 1 Database: MEDLINE Main subject: Powders / Triazoles / Bentonite / Colitis, Ulcerative / Aniline Compounds Type of study: Prognostic_studies Limits: Animals Language: En Year: 2020 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Powders / Triazoles / Bentonite / Colitis, Ulcerative / Aniline Compounds Type of study: Prognostic_studies Limits: Animals Language: En Year: 2020 Type: Article