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A pilot trial of complement inhibition using eculizumab to overcome platelet transfusion refractoriness in human leukocyte antigen allo-immunized patients.
Vo, Phuong; Purev, Enkhtsetseg; West, Kamille A; McDuffee, Emily; Worthy, Tatyana; Cook, Lisa; Hawks, Geri; Wells, Brian; Shalabi, Reem; Flegel, Willy A; Adams, Sharon D; Reger, Robert; Aue, Georg; Tian, Xin; Childs, Richard.
Affiliation
  • Vo P; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Purev E; University of Colorado, Denver, CO, USA.
  • West KA; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, USA.
  • McDuffee E; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Worthy T; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Cook L; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Hawks G; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Wells B; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Shalabi R; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Flegel WA; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, USA.
  • Adams SD; Department of Transfusion Medicine, NIH Clinical Center, National Institutes of Health, Bethesda, MD, USA.
  • Reger R; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Aue G; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Tian X; Office of Biostatistics Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
  • Childs R; Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Br J Haematol ; 189(3): 551-558, 2020 05.
Article in En | MEDLINE | ID: mdl-32086819
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Full text: 1 Database: MEDLINE Main subject: Immunization / Platelet Transfusion / Antibodies, Monoclonal, Humanized / HLA Antigens Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2020 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Immunization / Platelet Transfusion / Antibodies, Monoclonal, Humanized / HLA Antigens Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2020 Type: Article