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Enantiomer specific pharmacokinetics of ibuprofen in preterm neonates with patent ductus arteriosus.
Engbers, Aline G J; Flint, Robert B; Völler, Swantje; de Klerk, Johan C A; Reiss, Irwin K M; Andriessen, Peter; Liem, Kian D; Degraeuwe, Pieter L J; Croubels, Siska; Millecam, Joske; Allegaert, Karel; Simons, Sinno H P; Knibbe, Catherijne A J.
Affiliation
  • Engbers AGJ; Division of Systems Biomedicine & Pharmacology, LACDR, Leiden University, Leiden, the Netherlands.
  • Flint RB; Department of Paediatrics, Division of Neonatology, Erasmus UMC - Sophia Children's Hospital, Rotterdam, the Netherlands.
  • Völler S; Department of Paediatrics, Division of Neonatology, Erasmus UMC - Sophia Children's Hospital, Rotterdam, the Netherlands.
  • de Klerk JCA; Department of Pharmacy, Radboud University Medical Centre, Nijmegen, the Netherlands.
  • Reiss IKM; Department of Pharmacy, Erasmus MC, Rotterdam, The Netherlands.
  • Andriessen P; Division of Systems Biomedicine & Pharmacology, LACDR, Leiden University, Leiden, the Netherlands.
  • Liem KD; Division of BioTherapeutics, LACDR, Leiden University, Leiden, the Netherlands.
  • Degraeuwe PLJ; Department of Paediatrics, Division of Neonatology, Erasmus UMC - Sophia Children's Hospital, Rotterdam, the Netherlands.
  • Croubels S; Department of Paediatrics, Division of Neonatology, Erasmus UMC - Sophia Children's Hospital, Rotterdam, the Netherlands.
  • Millecam J; Department of Neonatology, Máxima Medical Centre, Veldhoven, the Netherlands.
  • Allegaert K; Department of Neonatology, Radboud University Medical Centre, Nijmegen, the Netherlands.
  • Simons SHP; Department of Paediatrics, Division of Neonatology, Maastricht University Medical Centre, the Netherlands.
  • Knibbe CAJ; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Belgium.
Br J Clin Pharmacol ; 86(10): 2028-2039, 2020 10.
Article in En | MEDLINE | ID: mdl-32250464
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Full text: 1 Database: MEDLINE Main subject: Ibuprofen / Ductus Arteriosus, Patent Type of study: Guideline Limits: Humans / Infant / Newborn Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Ibuprofen / Ductus Arteriosus, Patent Type of study: Guideline Limits: Humans / Infant / Newborn Language: En Year: 2020 Type: Article