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Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model.
Holland, Dominic; Frei, Oleksandr; Desikan, Rahul; Fan, Chun-Chieh; Shadrin, Alexey A; Smeland, Olav B; Sundar, V S; Thompson, Paul; Andreassen, Ole A; Dale, Anders M.
Affiliation
  • Holland D; Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, California, United States of America.
  • Frei O; Department of Neurosciences, University of California, San Diego, La Jolla, California, United States of America.
  • Desikan R; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Fan CC; Department of Radiology, University of California, San Francisco, San Francisco, California, United States of America.
  • Shadrin AA; Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, California, United States of America.
  • Smeland OB; Department of Radiology, University of California, San Diego, La Jolla, California, United States of America.
  • Sundar VS; Department of Cognitive Sciences, University of California at San Diego, La Jolla, California, United States of America.
  • Thompson P; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Andreassen OA; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
  • Dale AM; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
PLoS Genet ; 16(5): e1008612, 2020 05.
Article in En | MEDLINE | ID: mdl-32427991
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Full text: 1 Database: MEDLINE Main subject: Genetic Heterogeneity / Polymorphism, Single Nucleotide / Inheritance Patterns / Genetic Association Studies / Models, Genetic Limits: Humans Language: En Year: 2020 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Genetic Heterogeneity / Polymorphism, Single Nucleotide / Inheritance Patterns / Genetic Association Studies / Models, Genetic Limits: Humans Language: En Year: 2020 Type: Article