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ß-sitosterol ameliorates influenza A virus-induced proinflammatory response and acute lung injury in mice by disrupting the cross-talk between RIG-I and IFN/STAT signaling.
Zhou, Bei-Xian; Li, Jing; Liang, Xiao-Li; Pan, Xi-Ping; Hao, Yan-Bing; Xie, Pei-Fang; Jiang, Hai-Ming; Yang, Zi-Feng; Zhong, Nan-Shan.
Affiliation
  • Zhou BX; Department of Pharmacy, The People's Hospital of Gaozhou, Gaozhou, 525200, China.
  • Li J; State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Liang XL; State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Pan XP; Institute of Combination Chinese and Western Medicine, Guangzhou Medical University, Guangzhou, 511436, China.
  • Hao YB; State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Xie PF; State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Jiang HM; State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
  • Yang ZF; State Key Laboratory of Respiratory Disease, National Clinical Research Center of Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. Jeffyah@163.com.
  • Zhong NS; State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau, SAR, China. Jeffyah@163.com.
Acta Pharmacol Sin ; 41(9): 1178-1196, 2020 Sep.
Article in En | MEDLINE | ID: mdl-32504068
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Sitosterols / Signal Transduction / Acute Lung Injury / DEAD Box Protein 58 / Inflammation Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Antiviral Agents / Sitosterols / Signal Transduction / Acute Lung Injury / DEAD Box Protein 58 / Inflammation Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Year: 2020 Type: Article