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Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.
Khanna, Avinash; Côté, Alexandre; Arora, Shilpi; Moine, Ludivine; Gehling, Victor S; Brenneman, Jehrod; Cantone, Nico; Stuckey, Jacob I; Apte, Shruti; Ramakrishnan, Ashwin; Bruderek, Kamil; Bradley, William D; Audia, James E; Cummings, Richard T; Sims, Robert J; Trojer, Patrick; Levell, Julian R.
Affiliation
  • Khanna A; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Côté A; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Arora S; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Moine L; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Gehling VS; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Brenneman J; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Cantone N; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Stuckey JI; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Apte S; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Ramakrishnan A; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Bruderek K; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Bradley WD; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Audia JE; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Cummings RT; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Sims RJ; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Trojer P; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
  • Levell JR; Constellation Pharmaceuticals 215 First Street Suite 200, Cambridge, Massachusetts 02142, United States.
ACS Med Chem Lett ; 11(6): 1205-1212, 2020 Jun 11.
Article in En | MEDLINE | ID: mdl-32551002
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Full text: 1 Database: MEDLINE Type of study: Prognostic_studies Language: En Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Type of study: Prognostic_studies Language: En Year: 2020 Type: Article