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Lentigo maligna melanoma in situ with neurotropism.
Occidental, Michael; Shapiro, Richard; Jour, George.
Affiliation
  • Occidental M; Department of Pathology, New York University Langone Health, New York, New York, USA.
  • Shapiro R; Department of Surgery, New York University Langone Health, New York, New York, USA.
  • Jour G; Department of Pathology, New York University Langone Health, New York, New York, USA.
J Cutan Pathol ; 47(12): 1155-1158, 2020 Dec.
Article in En | MEDLINE | ID: mdl-32557727
ABSTRACT
Perineural invasion, or neurotropism, is defined by the presence of cancer cells either within the neuronal sheath or found along the nerves. In melanoma, it is most commonly associated with invasive desmoplastic melanoma, a melanoma that is most commonly associated with malignant melanoma in situ, lentigo maligna type. Initially, perineural invasion was included in the reported Breslow thickness; however, recent data suggest that it should not be included. In this report, we describe a case of malignant melanoma in situ, lentigo maligna type, with associated neurotropism in the absence of invasive component.
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Full text: 1 Database: MEDLINE Main subject: Hutchinson's Melanotic Freckle / Melanoma / Neoplasm Invasiveness / Nerve Fibers Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Year: 2020 Type: Article

Full text: 1 Database: MEDLINE Main subject: Hutchinson's Melanotic Freckle / Melanoma / Neoplasm Invasiveness / Nerve Fibers Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Humans / Male Language: En Year: 2020 Type: Article