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Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins.
Lee, Hunsang; Beilhartz, Greg L; Kucharska, Iga; Raman, Swetha; Cui, Hong; Lam, Mandy Hiu Yi; Liang, Huazhu; Rubinstein, John L; Schramek, Daniel; Julien, Jean-Philippe; Melnyk, Roman A; Taipale, Mikko.
Affiliation
  • Lee H; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
  • Beilhartz GL; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.
  • Kucharska I; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.
  • Raman S; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.
  • Cui H; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada.
  • Lam MHY; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.
  • Liang H; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Rubinstein JL; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Schramek D; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Julien JP; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada; Molecular Architecture of Life
  • Melnyk RA; Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: roman.melnyk@sickkids.ca.
  • Taipale M; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Molecular Architecture of Life Program, Canadian Institute for Advanced Research (CIFAR), Toronto, ON M5G
Cell ; 182(2): 345-356.e16, 2020 07 23.
Article in En | MEDLINE | ID: mdl-32589945

Full text: 1 Database: MEDLINE Main subject: Bacterial Toxins / Semaphorins / Clostridium sordellii Limits: Animals / Female / Humans Language: En Year: 2020 Type: Article

Full text: 1 Database: MEDLINE Main subject: Bacterial Toxins / Semaphorins / Clostridium sordellii Limits: Animals / Female / Humans Language: En Year: 2020 Type: Article