Adding the oxygen carrier M101 to a cold-storage solution could be an alternative to HOPE for liver graft preservation.

Alix, Pierre; Val-Laillet, David; Turlin, Bruno; Ben Mosbah, Ismail; Burel, Agnes; Bobillier, Eric; Bendavid, Claude; Delpy, Eric; Zal, Franck; Corlu, Anne; Boudjema, Karim

Alix, Pierre; Val-Laillet, David; Turlin, Bruno; Ben Mosbah, Ismail; Burel, Agnes; Bobillier, Eric; Bendavid, Claude; Delpy, Eric; Zal, Franck; Corlu, Anne; Boudjema, Karim.

Affiliation

Alix P; Service de Chirurgie Hépatobiliaire et Digestive, CHU Rennes, Université de Rennes, Rennes, France.
Val-Laillet D; INRAE, INSERM, Université de Rennes, Nutrition Metabolisms and Cancer, Rennes, St Gilles, France.
Turlin B; INRAE, INSERM, Université de Rennes, Nutrition Metabolisms and Cancer, Rennes, St Gilles, France.
Ben Mosbah I; Service d'Anatomie et de Cytologie Pathologiques, CHU Rennes, Université de Rennes, Rennes, France.
Burel A; Biopredic International, Saint-Grégoire, France.
Bobillier E; Plateforme Microscopie Electronique, MRic, BIOSIT UMS 3480, Université de Rennes, Rennes, France.
Bendavid C; INRAE, INSERM, Université de Rennes, Nutrition Metabolisms and Cancer, Rennes, St Gilles, France.
Delpy E; INRAE, INSERM, Université de Rennes, Nutrition Metabolisms and Cancer, Rennes, St Gilles, France.
Zal F; Laboratoire de Biochimie et Toxicologie, CHU Rennes, Université de Rennes, Rennes, France.
Corlu A; HEMARINA, Aéropôle Centre, Morlaix, France.
Boudjema K; HEMARINA, Aéropôle Centre, Morlaix, France.

JHEP Rep ; 2(4): 100119, 2020 Aug.

Article in En | MEDLINE | ID: mdl-32695967

Key words

ALT, alanine aminotransferase; AST, aspartate aminotransferase; Cell necrosis; DCD, deceased after circulatory death; DGF, delayed graft function; HOPE, hypothermic oxygenated machine perfusion; Haemoglobin; Hepatocyte; INR, international normalised ratio; IRI, ischaemia-reperfusion injury; Inflammation; Liver transplantation; Oxidative stress; PT, prothrombin time; SCS, simple cold-storage solutions; UWCSS, University of Wisconsin cold-storage solution

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