Control of Innate Immunity by Sialic Acids in the Nervous Tissue.

Liao, Huan; Klaus, Christine; Neumann, Harald

Liao, Huan; Klaus, Christine; Neumann, Harald.

Affiliation

Liao H; Neural Regeneration, Institute of Reconstructive Neurobiology, Medical Faculty and University Hospital of Bonn, University of Bonn, Venusberg-Campus 1, D-53127 Bonn, Germany.
Klaus C; Neural Regeneration, Institute of Reconstructive Neurobiology, Medical Faculty and University Hospital of Bonn, University of Bonn, Venusberg-Campus 1, D-53127 Bonn, Germany.
Neumann H; Neural Regeneration, Institute of Reconstructive Neurobiology, Medical Faculty and University Hospital of Bonn, University of Bonn, Venusberg-Campus 1, D-53127 Bonn, Germany.

Int J Mol Sci ; 21(15)2020 Jul 31.

Article in En | MEDLINE | ID: mdl-32752058

Subject(s)

Immunity, Innate/genetics; Nerve Tissue/metabolism; Sialic Acids/genetics; Sialyltransferases/genetics; Glycoconjugates/genetics; Glycoconjugates/immunology; Humans; Macrophages; Microglia/immunology; Microglia/metabolism; Nerve Tissue/immunology; Neurons/metabolism; Neurons/pathology; Phagocytosis/genetics; Sialic Acids/immunology; Sialic Acids/metabolism; Sialyltransferases/immunology

Key words

SIGLEC; aging; complement; desialylation; microglia; neurodegeneration; neuroinflammation; sialic acid

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Full text: 1 Database: MEDLINE Main subject: Sialic Acids / Sialyltransferases / Immunity, Innate / Nerve Tissue Limits: Humans Language: En Year: 2020 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Sialic Acids / Sialyltransferases / Immunity, Innate / Nerve Tissue Limits: Humans Language: En Year: 2020 Type: Article