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Early Clinical Experience With AZD4831, A Novel Myeloperoxidase Inhibitor, Developed for Patients With Heart Failure With Preserved Ejection Fraction.
Nelander, Karin; Lagerstrom-Fermer, Maria; Amilon, Carl; Michaëlsson, Erik; Heijer, Maria; Kjaer, Magnus; Russell, Muir; Han, David; Lindstedt, Eva-Lotte; Whatling, Carl; Gan, Li-Ming; Ericsson, Hans.
Affiliation
  • Nelander K; Early Biometrics and Statistical Innovation, Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Lagerstrom-Fermer M; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Amilon C; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Michaëlsson E; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Heijer M; Clinical Pharmacology Biologics and Bioanalysis, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Kjaer M; Early Biometrics and Statistical Innovation, Data Science and AI, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Russell M; Study Delivery, Early Oncology Clinical, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Han D; PAREXEL Early Phase Clinical Unit, Los Angeles, California, USA.
  • Lindstedt EL; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Whatling C; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Gan LM; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Ericsson H; Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Clin Transl Sci ; 14(3): 812-819, 2021 05.
Article in En | MEDLINE | ID: mdl-32770730
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Full text: 1 Database: MEDLINE Main subject: Pyrimidines / Pyrroles / Peroxidase / Heart Failure Type of study: Clinical_trials Limits: Adult / Humans / Male / Middle aged Language: En Year: 2021 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Pyrimidines / Pyrroles / Peroxidase / Heart Failure Type of study: Clinical_trials Limits: Adult / Humans / Male / Middle aged Language: En Year: 2021 Type: Article