Effect of change in cell substrate on the critical quality attributes of L-Zagreb Mumps vaccine manufactured using parallel plate bioreactor.

Muley, Ravindra; Dhere, Rajeev

Muley, Ravindra; Dhere, Rajeev.

Affiliation

Muley R; Serum Institute of India Pvt. Ltd., Hadapsar, Pune, 411 028, India; Symbiosis International (Deemed University), Lavale, Pune, 412 115, India.
Dhere R; Serum Institute of India Pvt. Ltd., Hadapsar, Pune, 411 028, India; Symbiosis International (Deemed University), Lavale, Pune, 412 115, India. Electronic address: rajeev.dhere@seruminstitute.com.

Biologicals ; 67: 29-37, 2020 Sep.

Article in En | MEDLINE | ID: mdl-32855039

Subject(s)

Bioreactors; Mumps Vaccine/immunology; Mumps virus/immunology; Mumps/immunology; Animals; Cell Line; Chlorocebus aethiops; Freeze Drying/methods; Humans; Mumps/prevention & control; Mumps/virology; Mumps Vaccine/administration & dosage; Mumps Vaccine/standards; Mumps virus/genetics; Mumps virus/physiology; Quality Control; Vaccination; Vaccines, Attenuated/administration & dosage; Vaccines, Attenuated/immunology; Vaccines, Attenuated/standards; Vero Cells; Virus Cultivation/instrumentation; Virus Cultivation/methods

Key words

CQA; L-Zagreb; MRC-5 cells; Mumps; Parallel Plate Bioreactor; Vero cells

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Full text: 1 Database: MEDLINE Main subject: Mumps Vaccine / Bioreactors / Mumps / Mumps virus Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2020 Type: Article

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