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Pediatric pan-central nervous system tumor analysis of immune-cell infiltration identifies correlates of antitumor immunity.
Grabovska, Yura; Mackay, Alan; O'Hare, Patricia; Crosier, Stephen; Finetti, Martina; Schwalbe, Edward C; Pickles, Jessica C; Fairchild, Amy R; Avery, Aimee; Cockle, Julia; Hill, Rebecca; Lindsey, Janet; Hicks, Debbie; Kristiansen, Mark; Chalker, Jane; Anderson, John; Hargrave, Darren; Jacques, Thomas S; Straathof, Karin; Bailey, Simon; Jones, Chris; Clifford, Steven C; Williamson, Daniel.
Affiliation
  • Grabovska Y; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Mackay A; Division of Molecular Pathology and Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK.
  • O'Hare P; Department of Paediatric Oncology, Great Ormond Street Hospital NHS Trust, London, UK.
  • Crosier S; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Finetti M; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Schwalbe EC; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Pickles JC; Developmental Biology and Cancer Programme, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Fairchild AR; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Avery A; Developmental Biology and Cancer Programme, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Cockle J; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Hill R; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Lindsey J; Division of Molecular Pathology and Division of Cancer Therapeutics, The Institute of Cancer Research, London, UK.
  • Hicks D; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Kristiansen M; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Chalker J; Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle Upon Tyne, UK.
  • Anderson J; UCL Genomics, UCL Great Ormond Street Institute of Child Health, London, UK.
  • Hargrave D; Specialist Integrated Haematology and Malignancy Diagnostic Service-Acquired Genomics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Jacques TS; Department of Paediatric Oncology, Great Ormond Street Hospital NHS Trust, London, UK.
  • Straathof K; Developmental Biology and Cancer Programme, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Bailey S; Department of Paediatric Oncology, Great Ormond Street Hospital NHS Trust, London, UK.
  • Jones C; Developmental Biology and Cancer Programme, University College London Great Ormond Street Institute of Child Health, London, UK.
  • Clifford SC; Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Williamson D; Department of Paediatric Oncology, Great Ormond Street Hospital NHS Trust, London, UK.
Nat Commun ; 11(1): 4324, 2020 08 28.
Article in En | MEDLINE | ID: mdl-32859926
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Full text: 1 Database: MEDLINE Main subject: Central Nervous System Neoplasms / Tumor Microenvironment / Immunotherapy Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Humans Language: En Year: 2020 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Central Nervous System Neoplasms / Tumor Microenvironment / Immunotherapy Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Humans Language: En Year: 2020 Type: Article