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RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
Spit, Maureen; Fenderico, Nicola; Jordens, Ingrid; Radaszkiewicz, Tomasz; Lindeboom, Rik Gh; Bugter, Jeroen M; Cristobal, Alba; Ootes, Lars; van Osch, Max; Janssen, Eline; Boonekamp, Kim E; Hanakova, Katerina; Potesil, David; Zdrahal, Zbynek; Boj, Sylvia F; Medema, Jan Paul; Bryja, Vitezslav; Koo, Bon-Kyoung; Vermeulen, Michiel; Maurice, Madelon M.
Affiliation
  • Spit M; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Fenderico N; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Jordens I; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Radaszkiewicz T; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
  • Lindeboom RG; Department of Molecular Biology and Oncode Institute, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.
  • Bugter JM; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Cristobal A; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Ootes L; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • van Osch M; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Janssen E; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Boonekamp KE; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Hanakova K; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
  • Potesil D; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
  • Zdrahal Z; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
  • Boj SF; Hubrecht Organoid Technology, Utrecht, The Netherlands.
  • Medema JP; Laboratory for Experimental Oncology and Radiobiology and Oncode Institute, Center for Experimental and Molecular Medicine, Amsterdam UMC, Cancer Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands.
  • Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
  • Koo BK; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Vermeulen M; Department of Molecular Biology and Oncode Institute, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.
  • Maurice MM; Department of Cell Biology and Oncode Institute, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
EMBO J ; 39(18): e103932, 2020 09 15.
Article in En | MEDLINE | ID: mdl-32965059

Full text: 1 Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Casein Kinase I / Wnt Signaling Pathway / Neoplasms Limits: Humans Language: En Year: 2020 Type: Article

Full text: 1 Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Casein Kinase I / Wnt Signaling Pathway / Neoplasms Limits: Humans Language: En Year: 2020 Type: Article