Airway Deposition of Extrafine Inhaled Triple Therapy in Patients with COPD: A Model Approach Based on Functional Respiratory Imaging Computer Simulations.

Usmani, Omar S; Scichilone, Nicola; Mignot, Benjamin; Belmans, Dennis; Van Holsbeke, Cedric; De Backer, Jan; De Maria, Roberta; Cuoghi, Erika; Topole, Eva; Georges, George

Usmani, Omar S; Scichilone, Nicola; Mignot, Benjamin; Belmans, Dennis; Van Holsbeke, Cedric; De Backer, Jan; De Maria, Roberta; Cuoghi, Erika; Topole, Eva; Georges, George.

Affiliation

Usmani OS; Airway Disease Section, National Heart and Lung Institute, Imperial College, London, UK.
Scichilone N; PROMISE Department of Medicine, University of Palermo, Palermo, Italy.
Mignot B; FLUIDDA, Kontich, Belgium.
Belmans D; FLUIDDA, Kontich, Belgium.
Van Holsbeke C; FLUIDDA, Kontich, Belgium.
De Backer J; FLUIDDA, Kontich, Belgium.
De Maria R; Chiesi Farmaceutici, SpA, Parma, Italy.
Cuoghi E; Chiesi Farmaceutici, SpA, Parma, Italy.
Topole E; Chiesi Farmaceutici, SpA, Parma, Italy.
Georges G; Chiesi Farmaceutici, SpA, Parma, Italy.

Int J Chron Obstruct Pulmon Dis ; 15: 2433-2440, 2020.

Article in En | MEDLINE | ID: mdl-33116458

Subject(s)

Bronchodilator Agents; Pulmonary Disease, Chronic Obstructive; Administration, Inhalation; Bronchodilator Agents/adverse effects; Computer Simulation; Drug Combinations; Formoterol Fumarate/therapeutic use; Humans; Pulmonary Disease, Chronic Obstructive/diagnostic imaging; Pulmonary Disease, Chronic Obstructive/drug therapy

Key words

X-ray computed; dry powder inhalers; inhaled corticosteroid; long-acting beta2 agonist; long-acting muscarinic antagonist; metered dose inhalers; tomography

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Full text: 1 Database: MEDLINE Main subject: Bronchodilator Agents / Pulmonary Disease, Chronic Obstructive Type of study: Prognostic_studies Limits: Humans Language: En Year: 2020 Type: Article

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