Improved green biosynthesis of chitosan decorated Ag- and Co3O4-nanoparticles: A relationship between surface morphology, photocatalytic and biomedical applications.
Nanomedicine
; 32: 102331, 2021 02.
Article
in En
| MEDLINE
| ID: mdl-33181272
ABSTRACT
AgNPs@Chitosan and Co3O4-NPs@Chitosan were fabricated with Salvia hispanica. Results showed MZI values of 5 and 30â¯mm for Co3O4-NPs- and AgNPs@Chitosan against S. aureus, and 15 and 21â¯mm for Co3O4-NPs- and AgNPs@Chitosan against E. coli (24â¯h, 20⯵g/mL), respectively. MTT assays showed up to 80% and 90%, 71% and 75%, and 91% and 94% mammalian cell viability for the green synthesized, chemically synthesized AgNPs and green synthesized AgNPs@Chitosan for HEK-293 and PC12 cells, respectively, and 70% and 71%, 59% and 62%, and 88% and 73% for the related Co3O4-NPs (24â¯h, 20⯵g/mL). The photocatalytic activities showed dye degradation after 135 and 105â¯min for AgNPs@Chitosan and Co3O4-NPs@Chitosan, respectively. FESEM results showed differences in particle sizes (32⯱â¯3.0â¯nm for the AgNPs and 41⯱â¯3.0â¯nm for the Co3O4NPs) but AFM results showed lower roughness of the AgNPs@Chitosan (7.639⯱â¯0.85â¯nm) compared to Co3O4NPs@Chitosan (9.218⯱â¯0.93â¯nm), which resulted in potential biomedical applications.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Oxides
/
Silver
/
Cobalt
/
Biomedical Technology
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Chitosan
/
Metal Nanoparticles
/
Green Chemistry Technology
/
Light
Limits:
Animals
/
Humans
Language:
En
Year:
2021
Type:
Article