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Streptococcus co-opts a conformational lock in human plasminogen to facilitate streptokinase cleavage and bacterial virulence.
Ayinuola, Yetunde A; Brito-Robinson, Teresa; Ayinuola, Olawole; Beck, Julia E; Cruz-Topete, Diana; Lee, Shaun W; Ploplis, Victoria A; Castellino, Francis J.
Affiliation
  • Ayinuola YA; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
  • Brito-Robinson T; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
  • Ayinuola O; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA.
  • Beck JE; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
  • Cruz-Topete D; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
  • Lee SW; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
  • Ploplis VA; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA.
  • Castellino FJ; W. M. Keck Center for Transgene Research, University of Notre Dame, Notre Dame, Indiana, USA; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana, USA. Electronic address: fcastell@nd.edu.
J Biol Chem ; 296: 100099, 2021.
Article in En | MEDLINE | ID: mdl-33208461
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Full text: 1 Database: MEDLINE Main subject: Plasminogen / Streptokinase / Bacterial Proteins Limits: Animals / Humans Language: En Year: 2021 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Plasminogen / Streptokinase / Bacterial Proteins Limits: Animals / Humans Language: En Year: 2021 Type: Article