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Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.
Volz, Erik; Hill, Verity; McCrone, John T; Price, Anna; Jorgensen, David; O'Toole, Áine; Southgate, Joel; Johnson, Robert; Jackson, Ben; Nascimento, Fabricia F; Rey, Sara M; Nicholls, Samuel M; Colquhoun, Rachel M; da Silva Filipe, Ana; Shepherd, James; Pascall, David J; Shah, Rajiv; Jesudason, Natasha; Li, Kathy; Jarrett, Ruth; Pacchiarini, Nicole; Bull, Matthew; Geidelberg, Lily; Siveroni, Igor; Goodfellow, Ian; Loman, Nicholas J; Pybus, Oliver G; Robertson, David L; Thomson, Emma C; Rambaut, Andrew; Connor, Thomas R.
Affiliation
  • Volz E; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK. Electronic address: e.volz@imperial.ac.uk.
  • Hill V; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
  • McCrone JT; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
  • Price A; School of Biosciences, Cardiff University, Cardiff, UK.
  • Jorgensen D; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.
  • O'Toole Á; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
  • Southgate J; School of Biosciences, Cardiff University, Cardiff, UK; Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK.
  • Johnson R; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.
  • Jackson B; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
  • Nascimento FF; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.
  • Rey SM; Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK.
  • Nicholls SM; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
  • Colquhoun RM; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK.
  • da Silva Filipe A; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Shepherd J; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Pascall DJ; Institute of Biodiversity, Animal Health and Comparative Medicine, Boyd Orr Centre for Population and Ecosystem Health, University of Glasgow, Glasgow, UK.
  • Shah R; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Jesudason N; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Li K; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Jarrett R; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Pacchiarini N; Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK.
  • Bull M; Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK.
  • Geidelberg L; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.
  • Siveroni I; MRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.
  • Goodfellow I; Department of Pathology, University of Cambridge, Cambridge, UK.
  • Loman NJ; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
  • Pybus OG; Department of Zoology, University of Oxford, Oxford, UK; Department of Pathobiology and Population Sciences, The Royal Veterinary College, London, UK.
  • Robertson DL; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Thomson EC; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Rambaut A; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK. Electronic address: a.rambaut@ed.ac.uk.
  • Connor TR; School of Biosciences, Cardiff University, Cardiff, UK; Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK; Quadram Institute Bioscience, Norwich, UK. Electronic address: connortr@cardiff.ac.uk.
Cell ; 184(1): 64-75.e11, 2021 01 07.
Article in En | MEDLINE | ID: mdl-33275900
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Full text: 1 Database: MEDLINE Main subject: Amino Acid Substitution / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Limits: Humans Country/Region as subject: Europa Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Amino Acid Substitution / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Limits: Humans Country/Region as subject: Europa Language: En Year: 2021 Type: Article