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EP4 receptor agonist L-902688 augments cytotoxic activities of ibrutinib, idelalisib, and venetoclax against chronic lymphocytic leukemia cells.
Nabergoj, Sanja; Markovic, Tijana; Avsec, Damjan; Gobec, Martina; Podgornik, Helena; Jakopin, Ziga; Mlinaric-Rascan, Irena.
Affiliation
  • Nabergoj S; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Markovic T; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Avsec D; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Gobec M; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Podgornik H; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia; University Medical Centre Ljubljana, Department of Haematology, Ljubljana, Slovenia.
  • Jakopin Z; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
  • Mlinaric-Rascan I; University of Ljubljana, Faculty of Pharmacy, Askerceva cesta 7, 1000 Ljubljana, Slovenia. Electronic address: irena.mlinaric-rascan@ffa.uni-lj.si.
Biochem Pharmacol ; 183: 114352, 2021 01.
Article in En | MEDLINE | ID: mdl-33278351
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Full text: 1 Database: MEDLINE Main subject: Piperidines / Purines / Pyrrolidinones / Sulfonamides / Tetrazoles / Adenine / Leukemia, Lymphocytic, Chronic, B-Cell / Bridged Bicyclo Compounds, Heterocyclic / Quinazolinones / Receptors, Prostaglandin E, EP4 Subtype Limits: Adult / Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Piperidines / Purines / Pyrrolidinones / Sulfonamides / Tetrazoles / Adenine / Leukemia, Lymphocytic, Chronic, B-Cell / Bridged Bicyclo Compounds, Heterocyclic / Quinazolinones / Receptors, Prostaglandin E, EP4 Subtype Limits: Adult / Humans Language: En Year: 2021 Type: Article