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Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Yusufova, Nevin; Kloetgen, Andreas; Teater, Matt; Osunsade, Adewola; Camarillo, Jeannie M; Chin, Christopher R; Doane, Ashley S; Venters, Bryan J; Portillo-Ledesma, Stephanie; Conway, Joseph; Phillip, Jude M; Elemento, Olivier; Scott, David W; Béguelin, Wendy; Licht, Jonathan D; Kelleher, Neil L; Staudt, Louis M; Skoultchi, Arthur I; Keogh, Michael-Christopher; Apostolou, Effie; Mason, Christopher E; Imielinski, Marcin; Schlick, Tamar; David, Yael; Tsirigos, Aristotelis; Allis, C David; Soshnev, Alexey A; Cesarman, Ethel; Melnick, Ari M.
Affiliation
  • Yusufova N; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Kloetgen A; Cell and Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA.
  • Teater M; Department of Pathology, NYU School of Medicine, New York, NY, USA.
  • Osunsade A; Department of Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Camarillo JM; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Chin CR; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Doane AS; Tri-Institutional PhD Program in Chemical Biology, New York, NY, USA.
  • Venters BJ; Department of Chemistry, Northwestern University, Evanston, IL, USA.
  • Portillo-Ledesma S; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
  • Conway J; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA.
  • Phillip JM; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Elemento O; Tri-Institutional PhD Program in Computational Biomedicine, New York, NY, USA.
  • Scott DW; Tri-Institutional PhD Program in Computational Biomedicine, New York, NY, USA.
  • Béguelin W; Institute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Licht JD; EpiCypher, Durham, NC, USA.
  • Kelleher NL; Department of Chemistry, New York University, New York, NY, USA.
  • Staudt LM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Skoultchi AI; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Keogh MC; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Apostolou E; Centre for Lymphoid Cancer, BC Cancer, Vancouver, British Columbia, Canada.
  • Mason CE; Division of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
  • Imielinski M; University of Florida Health Cancer Center, The University of Florida Cancer and Genetics Research Complex, Gainesville, FL, USA.
  • Schlick T; Department of Chemistry, Northwestern University, Evanston, IL, USA.
  • David Y; Department of Molecular Biosciences, Northwestern University, Evanston, IL, USA.
  • Tsirigos A; Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA.
  • Allis CD; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Soshnev AA; Department of Cell Biology, Albert Einstein College of Medicine, New York, NY, USA.
  • Cesarman E; EpiCypher, Durham, NC, USA.
  • Melnick AM; Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Nature ; 589(7841): 299-305, 2021 01.
Article in En | MEDLINE | ID: mdl-33299181
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Full text: 1 Database: MEDLINE Main subject: Chromatin / Histones / Cell Transformation, Neoplastic / Lymphoma Limits: Animals / Humans Language: En Year: 2021 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Chromatin / Histones / Cell Transformation, Neoplastic / Lymphoma Limits: Animals / Humans Language: En Year: 2021 Type: Article