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Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.
Lemieux, Jacob E; Siddle, Katherine J; Shaw, Bennett M; Loreth, Christine; Schaffner, Stephen F; Gladden-Young, Adrianne; Adams, Gordon; Fink, Timelia; Tomkins-Tinch, Christopher H; Krasilnikova, Lydia A; DeRuff, Katherine C; Rudy, Melissa; Bauer, Matthew R; Lagerborg, Kim A; Normandin, Erica; Chapman, Sinéad B; Reilly, Steven K; Anahtar, Melis N; Lin, Aaron E; Carter, Amber; Myhrvold, Cameron; Kemball, Molly E; Chaluvadi, Sushma; Cusick, Caroline; Flowers, Katelyn; Neumann, Anna; Cerrato, Felecia; Farhat, Maha; Slater, Damien; Harris, Jason B; Branda, John A; Hooper, David; Gaeta, Jessie M; Baggett, Travis P; O'Connell, James; Gnirke, Andreas; Lieberman, Tami D; Philippakis, Anthony; Burns, Meagan; Brown, Catherine M; Luban, Jeremy; Ryan, Edward T; Turbett, Sarah E; LaRocque, Regina C; Hanage, William P; Gallagher, Glen R; Madoff, Lawrence C; Smole, Sandra; Pierce, Virginia M; Rosenberg, Eric.
Affiliation
  • Lemieux JE; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA. lemieux@broadinstitute.org pardis@broadinstitute.org bronwyn@broadinstitute.org.
  • Siddle KJ; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
  • Shaw BM; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Loreth C; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • Schaffner SF; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Gladden-Young A; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
  • Adams G; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Fink T; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Tomkins-Tinch CH; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • Krasilnikova LA; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA, USA.
  • DeRuff KC; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Rudy M; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Bauer MR; Massachusetts Department of Public Health, Boston, MA, USA.
  • Lagerborg KA; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Normandin E; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • Chapman SB; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Reilly SK; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • Anahtar MN; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Lin AE; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Carter A; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Myhrvold C; Harvard Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.
  • Kemball ME; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Chaluvadi S; Harvard Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.
  • Cusick C; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Flowers K; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Neumann A; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Cerrato F; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Farhat M; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • Slater D; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Harris JB; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Branda JA; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • Hooper D; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Gaeta JM; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Baggett TP; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.
  • O'Connell J; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Gnirke A; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Lieberman TD; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Philippakis A; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Burns M; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Brown CM; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Luban J; Broad Institute of Harvard and MIT, 415 Main Street, Cambridge, MA 02142, USA.
  • Ryan ET; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Turbett SE; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, MA, USA.
  • LaRocque RC; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
  • Hanage WP; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
  • Gallagher GR; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.
  • Madoff LC; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Smole S; Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.
  • Pierce VM; Institute for Research, Quality, and Policy in Homeless Health Care, Boston Health Care for the Homeless Program, Boston, MA, USA.
  • Rosenberg E; Section of General Internal Medicine, Boston University Medical Center, Boston, MA, USA.
Science ; 371(6529)2021 02 05.
Article in En | MEDLINE | ID: mdl-33303686
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Full text: 1 Database: MEDLINE Main subject: Phylogeny / Genome, Viral / SARS-CoV-2 / COVID-19 Type of study: Screening_studies Limits: Humans Country/Region as subject: America do norte Language: En Year: 2021 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Phylogeny / Genome, Viral / SARS-CoV-2 / COVID-19 Type of study: Screening_studies Limits: Humans Country/Region as subject: America do norte Language: En Year: 2021 Type: Article