PLEKHG4B enables actin cytoskeletal remodeling during epithelial cell-cell junction formation.

Ninomiya, Komaki; Ohta, Kai; Yamashita, Kazunari; Mizuno, Kensaku; Ohashi, Kazumasa.

Affiliation

Ninomiya K; Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Ohta K; Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Yamashita K; Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Mizuno K; Department of Chemistry, Graduate School of Science, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan.
Ohashi K; Laboratory of Molecular and Cellular Biology, Graduate School of Life Sciences, Tohoku University, Aobayama, Sendai, Miyagi 980-8578, Japan kmizuno@biology.tohoku.ac.jp kazumasa.ohashi.b2@tohoku.ac.jp.

J Cell Sci ; 134(2)2021 01 27.

Article in En | MEDLINE | ID: mdl-33310911

Subject(s)

Actins; Intercellular Junctions; Actins/genetics; Actins/metabolism; Cytoskeleton/metabolism; Epithelial Cells/metabolism; Guanine Nucleotide Exchange Factors/genetics; Guanine Nucleotide Exchange Factors/metabolism; Intercellular Junctions/metabolism; Rho Guanine Nucleotide Exchange Factors/genetics; rhoA GTP-Binding Protein/genetics; rhoA GTP-Binding Protein/metabolism

Key words

Actin organization; Annexin-A2; Cell adhesion; Myosin; PLEKHG4B; Rho-GEF