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Dual Inhibition of MEK and AXL Targets Tumor Cell Heterogeneity and Prevents Resistant Outgrowth Mediated by the Epithelial-to-Mesenchymal Transition in NSCLC.
Konen, Jessica M; Rodriguez, B Leticia; Padhye, Aparna; Ochieng, Joshua K; Gibson, Laura; Diao, Lixia; Fowlkes, Natalie W; Fradette, Jared J; Peng, David H; Cardnell, Robert J; Kovacs, Jeffrey J; Wang, Jing; Byers, Lauren A; Gibbons, Don L.
Affiliation
  • Konen JM; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rodriguez BL; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Padhye A; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Ochieng JK; MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, Texas.
  • Gibson L; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Diao L; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Fowlkes NW; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Fradette JJ; Department of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Peng DH; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Cardnell RJ; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kovacs JJ; Oncology & Angiogenesis, Regeneron Pharmaceuticals, Inc., Tarrytown, New York.
  • Wang J; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Byers LA; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Gibbons DL; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Cancer Res ; 81(5): 1398-1412, 2021 03 01.
Article in En | MEDLINE | ID: mdl-33402388
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Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins / Receptor Protein-Tyrosine Kinases / Carcinoma, Non-Small-Cell Lung / Mitogen-Activated Protein Kinase Kinases / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Proto-Oncogene Proteins / Receptor Protein-Tyrosine Kinases / Carcinoma, Non-Small-Cell Lung / Mitogen-Activated Protein Kinase Kinases / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2021 Type: Article