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Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol.
Polanco, Juan Carlos; Hand, Gabriel Rhys; Briner, Adam; Li, Chuanzhou; Götz, Jürgen.
Affiliation
  • Polanco JC; Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), The University of Queensland, Brisbane, QLD, 4072, Australia. j.polanco@uq.edu.au.
  • Hand GR; Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Briner A; Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Li C; Department of Medical Genetics, School of Basic Medicine and Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
  • Götz J; Clem Jones Centre for Ageing Dementia Research (CJCADR), Queensland Brain Institute (QBI), The University of Queensland, Brisbane, QLD, 4072, Australia. j.goetz@uq.edu.au.
Acta Neuropathol ; 141(2): 235-256, 2021 02.
Article in En | MEDLINE | ID: mdl-33417012
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Full text: 1 Database: MEDLINE Main subject: Tau Proteins / Cytosol / Exosomes / Lysosomes Limits: Animals / Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Tau Proteins / Cytosol / Exosomes / Lysosomes Limits: Animals / Humans Language: En Year: 2021 Type: Article