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Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages.
Wauters, Els; Van Mol, Pierre; Garg, Abhishek Dinkarnath; Jansen, Sander; Van Herck, Yannick; Vanderbeke, Lore; Bassez, Ayse; Boeckx, Bram; Malengier-Devlies, Bert; Timmerman, Anna; Van Brussel, Thomas; Van Buyten, Tina; Schepers, Rogier; Heylen, Elisabeth; Dauwe, Dieter; Dooms, Christophe; Gunst, Jan; Hermans, Greet; Meersseman, Philippe; Testelmans, Dries; Yserbyt, Jonas; Tejpar, Sabine; De Wever, Walter; Matthys, Patrick; Neyts, Johan; Wauters, Joost; Qian, Junbin; Lambrechts, Diether.
Affiliation
  • Wauters E; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
  • Van Mol P; Department of Pneumology, University Hospitals Leuven, Leuven, Belgium.
  • Garg AD; Department of Pneumology, University Hospitals Leuven, Leuven, Belgium.
  • Jansen S; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Van Herck Y; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Vanderbeke L; Laboratory for Cell Stress & Immunity (CSI), Department of Cellular and Molecular Medicine (CMM), KU Leuven, Leuven, Belgium.
  • Bassez A; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.
  • Boeckx B; Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven, Belgium.
  • Malengier-Devlies B; Laboratory of Clinical Bacteriology and Mycology, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
  • Timmerman A; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Van Brussel T; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Van Buyten T; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Schepers R; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Heylen E; Laboratory of Immunobiology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.
  • Dauwe D; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Dooms C; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Gunst J; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Hermans G; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Meersseman P; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.
  • Testelmans D; Laboratory of Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.
  • Yserbyt J; VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Tejpar S; Laboratory of Virology and Chemotherapy, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.
  • De Wever W; Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Matthys P; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
  • Neyts J; Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Wauters J; Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Qian J; Laboratory for Clinical Infectious and Inflammatory Disorders, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
  • Lambrechts D; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Cell Res ; 31(3): 272-290, 2021 03.
Article in En | MEDLINE | ID: mdl-33473155
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Full text: 1 Database: MEDLINE Main subject: Bronchoalveolar Lavage / Adaptive Immunity / Single-Cell Analysis / COVID-19 / Immunity, Innate Type of study: Prognostic_studies Limits: Humans Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Bronchoalveolar Lavage / Adaptive Immunity / Single-Cell Analysis / COVID-19 / Immunity, Innate Type of study: Prognostic_studies Limits: Humans Language: En Year: 2021 Type: Article