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p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury Model.
Buitrago-Molina, Laura Elisa; Marhenke, Silke; Becker, Diana; Geffers, Robert; Itzel, Timo; Teufel, Andreas; Jaeschke, Hartmut; Lechel, André; Unger, Kristian; Markovic, Jovana; Sharma, Amar Deep; Marquardt, Jens U; Saborowski, Michael; Saborowski, Anna; Vogel, Arndt.
Affiliation
  • Buitrago-Molina LE; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Marhenke S; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Becker D; First Department of Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
  • Geffers R; Department of Cell Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Itzel T; Division of Hepatology, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Teufel A; Division of Hepatology, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Jaeschke H; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas.
  • Lechel A; Department of Internal Medicine I, University Hospital Ulm, Ulm, Germany.
  • Unger K; Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, Neuherberg, Germany.
  • Markovic J; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Sharma AD; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Marquardt JU; First Department of Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
  • Saborowski M; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Saborowski A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
  • Vogel A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany. Electronic address: vogel.arndt@mh-hannover.de.
Cell Mol Gastroenterol Hepatol ; 11(5): 1387-1404, 2021.
Article in En | MEDLINE | ID: mdl-33484913
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Full text: 1 Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Cyclin-Dependent Kinase Inhibitor p21 / Acute Lung Injury / Carcinogenesis / Checkpoint Kinase 2 / Liver Neoplasms / Liver Regeneration Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Cyclin-Dependent Kinase Inhibitor p21 / Acute Lung Injury / Carcinogenesis / Checkpoint Kinase 2 / Liver Neoplasms / Liver Regeneration Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article