Percutaneous thermal ablation of sacral metastases: Assessment of pain relief and local tumor control.
Diagn Interv Imaging
; 102(6): 355-361, 2021 Jun.
Article
in En
| MEDLINE
| ID: mdl-33487588
ABSTRACT
PURPOSE:
To retrospectively report on safety, pain relief and local tumor control achieved with percutaneous ablation of sacral bone metastases. MATERIALS ANDMETHODS:
From February 2009 to June 2020, 23 consecutive patients (12 women and 11 men; mean age, 60±8 [SD] years; median, 60; range 48-80 years) with 23 sacral metastases underwent radiofrequency (RFA) or cryo-ablation (CA), with palliative or curative intent at our institution. Patients' demographics and data pertaining to treated metastases, procedure-related variables, safety, and clinical evolution following ablation were collected and analyzed. Pain was assessed with numerical pain rating scale (NPRS).RESULTS:
Sixteen (70%) patients were treated with palliative and 7 (30%) with curative intent. Mean tumor diameter was 38±19 (SD) mm (median, 36; range 11-76). External radiation therapy had been performed on five metastases (5/23; 22%) prior to ablation. RFA was used in 9 (39%) metastases and CA in the remaining 14 (61%). Thermo-protective measures and adjuvant bone consolidation were used whilst treating 20 (87%) and 8 (35%) metastases, respectively. Five (22%) minor complications were recorded. At mean 31±21 (SD) (median, 32; range 2-70) months follow-up mean NPRS was 2±2 (SD) (median, 1; range 0-6) vs. 5±1 (median, 5; range 4-8; P<0.001) at the baseline. Three metastases out of 7 (43%) undergoing curative ablation showed local progression at mean 4±4 (SD) (median, 2; range 1-8) months follow-up.CONCLUSION:
Percutaneous ablation of sacral metastases is safe and results in significant long-lasting pain relief. Local tumor control seems sub-optimal; however, further investigations are needed to confirm these findings due to paucity of data.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Bone Neoplasms
/
Catheter Ablation
Type of study:
Observational_studies
Limits:
Female
/
Humans
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Male
/
Middle aged
Language:
En
Year:
2021
Type:
Article