Tyramine synthesis, vesicular packaging, and the SNARE complex function coordinately in astrocytes to regulate Drosophila alcohol sedation.

Lee, Kristen M; Talikoti, Ananya; Shelton, Keith; Grotewiel, Mike

Lee, Kristen M; Talikoti, Ananya; Shelton, Keith; Grotewiel, Mike.

Affiliation

Lee KM; Neuroscience Graduate Program, Virginia Commonwealth University, Richmond, Virginia, USA.
Talikoti A; Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, USA.
Shelton K; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
Grotewiel M; Neuroscience Graduate Program, Virginia Commonwealth University, Richmond, Virginia, USA.

Addict Biol ; 26(4): e13019, 2021 07.

Article in En | MEDLINE | ID: mdl-33538092

Subject(s)

Alcohol Drinking/metabolism; Astrocytes/metabolism; Drosophila/metabolism; SNARE Proteins/metabolism; Tyramine/biosynthesis; Vesicular Monoamine Transport Proteins/metabolism; Animals; Cytoplasm/metabolism; Dopamine/metabolism; Ethanol/metabolism; Female; Mixed Function Oxygenases; Neurons/metabolism; Octopamine/metabolism; Tyrosine Decarboxylase/metabolism

Key words

Drosophila; VMAT; alcohol; astrocytes; glia; tyramine

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Full text: 1 Database: MEDLINE Main subject: Alcohol Drinking / Tyramine / Astrocytes / Drosophila / Vesicular Monoamine Transport Proteins / SNARE Proteins Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article

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