The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression.

Nozaki, Tadasuke; Takahashi, Masayuki; Ishikawa, Tatsuya; Haino, Arisa; Seki, Mineaki; Kikuchi, Hidetomo; Yuan, Bo; Nashimoto, Masayuki.

Affiliation

Nozaki T; Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Horinouchi 1432-1, Hachioji, Tokyo, 192-0392, Japan.
Takahashi M; Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akihaku, Niigata, Niigata, 956-8603, Japan.
Ishikawa T; Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akihaku, Niigata, Niigata, 956-8603, Japan.
Haino A; Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akihaku, Niigata, Niigata, 956-8603, Japan.
Seki M; Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akihaku, Niigata, Niigata, 956-8603, Japan.
Kikuchi H; Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Horinouchi 1432-1, Hachioji, Tokyo, 192-0392, Japan.
Yuan B; Department of Clinical Molecular Genetics, Faculty of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Horinouchi 1432-1, Hachioji, Tokyo, 192-0392, Japan.
Nashimoto M; Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akihaku, Niigata, Niigata, 956-8603, Japan.

Biochem Biophys Rep ; 26: 100918, 2021 Jul.

Article in En | MEDLINE | ID: mdl-33553691