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A first-in-human study of 11C-MTP38, a novel PET ligand for phosphodiesterase 7.
Kubota, Manabu; Seki, Chie; Kimura, Yasuyuki; Takahata, Keisuke; Shimada, Hitoshi; Takado, Yuhei; Matsuoka, Kiwamu; Tagai, Kenji; Sano, Yasunori; Yamamoto, Yasuharu; Okada, Maki; Kikuchi, Tatsuya; Ichise, Masanori; Kawamura, Kazunori; Zhang, Ming-Rong; Higuchi, Makoto.
Affiliation
  • Kubota M; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan. kubota.manabu@qst.go.jp.
  • Seki C; Department of Psychiatry, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, Japan. kubota.manabu@qst.go.jp.
  • Kimura Y; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Takahata K; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Shimada H; Department of Clinical and Experimental Neuroimaging, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, 7-430 Morioka, Obu, Aichi, Japan.
  • Takado Y; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Matsuoka K; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan.
  • Tagai K; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Sano Y; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Yamamoto Y; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Okada M; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Kikuchi T; Department of Psychiatry, The Jikei University Graduate School of Medicine, Tokyo, 105-8461, Japan.
  • Ichise M; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Kawamura K; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan.
  • Zhang MR; Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage-ku, Chiba, Chiba, 263-8555, Japan.
  • Higuchi M; Department of Neuropsychiatry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan.
Eur J Nucl Med Mol Imaging ; 48(9): 2846-2855, 2021 08.
Article in En | MEDLINE | ID: mdl-33566152
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Full text: 1 Database: MEDLINE Main subject: Positron-Emission Tomography / Cyclic Nucleotide Phosphodiesterases, Type 7 Limits: Humans / Male Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Positron-Emission Tomography / Cyclic Nucleotide Phosphodiesterases, Type 7 Limits: Humans / Male Language: En Year: 2021 Type: Article