Targeting the neonatal Fc receptor (FcRn) to treat autoimmune diseases and maternal-fetal immune cytopenias.

Wyckoff, Sarah L; Hudson, Krystalyn E

Wyckoff, Sarah L; Hudson, Krystalyn E.

Affiliation

Wyckoff SL; Columbia University Irving Medical Center, New York, New York, USA.
Hudson KE; Columbia University Irving Medical Center, New York, New York, USA.

Transfusion ; 61(5): 1350-1354, 2021 05.

Article in En | MEDLINE | ID: mdl-33650699

Subject(s)

Autoimmune Diseases/drug therapy; Purpura, Thrombocytopenic, Idiopathic/drug therapy; Receptors, Fc/antagonists & inhibitors; Animals; Autoimmune Diseases/immunology; Autoimmunity/drug effects; Drug Development; Female; Fetus/immunology; Histocompatibility Antigens Class I/immunology; Humans; Immunoglobulin G/immunology; Molecular Targeted Therapy; Pregnancy; Purpura, Thrombocytopenic, Idiopathic/immunology; Receptors, Fc/immunology

Key words

AIHA/drug-induced IHA; HDN; immune thrombocytopenia

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Full text: 1 Database: MEDLINE Main subject: Autoimmune Diseases / Receptors, Fc / Purpura, Thrombocytopenic, Idiopathic Type of study: Prognostic_studies Limits: Animals / Female / Humans / Pregnancy Language: En Year: 2021 Type: Article

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