Thermal dosimetry of normal porcine tissue.
Radiat Res
; 114(2): 225-30, 1988 May.
Article
in En
| MEDLINE
| ID: mdl-3375426
ABSTRACT
The response of normal porcine fat and muscle to graduated doses of hyperthermia provided by an annularly focused acoustic source was measured. Temperatures and exposure times were varied between 43 degrees C (20-90 min), 45 and 47 degrees C (20-60 min), and 49 degrees C (20 min). Response, based on histologic grading of the treated sites 30 days after exposure, was found to correlate well when mapped against several methods of estimating thermal energy deposition. The threshold for damage production was at or near 43 degrees C. For a given temperature, a nearly exponential increase in relative tissue damage as a function of increased exposure time was found. A twofold increase in tissue damage was produced in fat relative to muscle at any given thermal dose.
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Database:
MEDLINE
Main subject:
Ultrasonic Therapy
/
Adipose Tissue
/
Muscles
Limits:
Animals
Language:
En
Year:
1988
Type:
Article