Your browser doesn't support javascript.
loading
Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid enhanced magnetic resonance imaging-guided risk assessment in living donor liver transplant patients with postoperative complications: a pilot study.
Kolu, M; Kahraman, A S; Akbulut, S; Yildirim, I O.
Affiliation
  • Kolu M; Department of Radiology, Harran University Faculty of Medicine, Sanliurfa, Turkey. drrdylg@gmail.com.
Eur Rev Med Pharmacol Sci ; 25(5): 2199-2205, 2021 03.
Article in En | MEDLINE | ID: mdl-33755957
ABSTRACT

OBJECTIVE:

To evaluate whether gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) enhanced magnetic resonance imaging (MRI), the measurements of quantitative and qualitative parameters on hepatobiliary phase images can predict the risk of postoperative complications in patients underwent living donor liver transplantation (LDLT) PATIENTS AND

METHODS:

We obtained Gd-EOB-DTPA-enhanced 3 Tesla MRI before living donor hepatectomy in donors (donor group; n=30) and after LDLT in their recipients (recipient group; n=30). MRIs were evaluated in terms of quantitative and qualitative variables. Quantitative parameters included relative liver enhancement value, biliary signal intensity value, and muscle signal index value. Qualitative parameters included visual evaluation of the liver and biliary enhancement on hepatobiliary phase images. Patients were followed up for postoperative biliary and vascular complications and divided according to the presence and absence of complications. The relationship between MRI parameters and postoperative complications was statistically analyzed.

RESULTS:

The mean relative liver enhancement values, mean biliary signal values, and muscle signal index were significantly lower in recipients with postoperative complications than those in donors and recipients without complications (p < 0.001). Visual assessments of liver enhancement and biliary signal were also significantly different in recipients with postoperative complications than that in donors and recipients without complications (p < 0.001).

CONCLUSIONS:

Quantitative and qualitative MRI parameters obtained by Gd-EOB-DTPA-enhanced MRI on hepatobiliary phase images may potentially become a reliable tool for the assessment of the risk for postoperative complications after LDLT.
Subject(s)

Full text: 1 Database: MEDLINE Main subject: Magnetic Resonance Imaging / Liver Transplantation / Living Donors / Gadolinium DTPA / Hepatitis, Viral, Human Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2021 Type: Article

Full text: 1 Database: MEDLINE Main subject: Magnetic Resonance Imaging / Liver Transplantation / Living Donors / Gadolinium DTPA / Hepatitis, Viral, Human Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2021 Type: Article