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Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2 S production.
Wang, Weiyun; Ren, Shaofang; Lu, Yunkun; Chen, Xi; Qu, Juanjuan; Ma, Xiaojie; Deng, Qian; Hu, Zhensheng; Jin, Yan; Zhou, Ziyu; Ge, Wenyan; Zhu, Yibing; Yang, Nannan; Li, Qin; Pu, Jiaqi; Chen, Guo; Ye, Cunqi; Wang, Hao; Zhao, Xiaoyang; Liu, Zhiqiang; Zhu, Saiyong.
Affiliation
  • Wang W; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Ren S; State Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Lu Y; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Chen X; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Qu J; College of Life Science, Shanxi University, Taiyuan, China.
  • Ma X; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Deng Q; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Hu Z; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Jin Y; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Zhou Z; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Ge W; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Zhu Y; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Yang N; Prenatal Diagnosis Center, Hangzhou Women's Hospital, Hangzhou, China.
  • Li Q; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Pu J; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Chen G; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Ye C; The MOE Key Laboratory of Biosystems Homeostasis & Protection and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.
  • Wang H; Prenatal Diagnosis Center, Hangzhou Women's Hospital, Hangzhou, China.
  • Zhao X; Department of Cell Biology and Medical Genetics, School of Medicine, Zhejiang University, Hangzhou, China.
  • Liu Z; State Key Laboratory of Organ Failure Research, Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
  • Zhu S; College of Life Science, Shanxi University, Taiyuan, China.
EMBO J ; 40(11): e106771, 2021 06 01.
Article in En | MEDLINE | ID: mdl-33909912
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Full text: 1 Database: MEDLINE Main subject: Fibroblasts / Syk Kinase / Hydrogen Sulfide Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Fibroblasts / Syk Kinase / Hydrogen Sulfide Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article