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Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine.
Sun, Yizhi; Rahbani, Janane F; Jedrychowski, Mark P; Riley, Christopher L; Vidoni, Sara; Bogoslavski, Dina; Hu, Bo; Dumesic, Phillip A; Zeng, Xing; Wang, Alex B; Knudsen, Nelson H; Kim, Caroline R; Marasciullo, Anthony; Millán, José L; Chouchani, Edward T; Kazak, Lawrence; Spiegelman, Bruce M.
Affiliation
  • Sun Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Rahbani JF; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Jedrychowski MP; Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.
  • Riley CL; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
  • Vidoni S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bogoslavski D; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Hu B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dumesic PA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Zeng X; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wang AB; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Knudsen NH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Kim CR; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Marasciullo A; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Millán JL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Chouchani ET; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
  • Kazak L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Spiegelman BM; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Nature ; 593(7860): 580-585, 2021 05.
Article in En | MEDLINE | ID: mdl-33981039
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Full text: 1 Database: MEDLINE Main subject: Phosphocreatine / Thermogenesis / Alkaline Phosphatase / Mitochondria Limits: Animals Language: En Year: 2021 Type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Phosphocreatine / Thermogenesis / Alkaline Phosphatase / Mitochondria Limits: Animals Language: En Year: 2021 Type: Article