PEGylation of mRNA by Hybridization of Complementary PEG-RNA Oligonucleotides Stabilizes mRNA without Using Cationic Materials.

Yoshinaga, Naoto; Naito, Mitsuru; Tachihara, Yoshihiro; Boonstra, Eger; Osada, Kensuke; Cabral, Horacio; Uchida, Satoshi.

Affiliation

Yoshinaga N; Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Naito M; RIKEN Center for Sustainable Resource Science, Wako 351-0198, Saitama, Japan.
Tachihara Y; Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Boonstra E; Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Osada K; Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.
Cabral H; National Institute of Radiological Science, 4-9-1 Anagawa, Inage-ku, Chiba-shi 236-8555, Chiba, Japan.
Uchida S; Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan.

Pharmaceutics ; 13(6)2021 May 27.

Article in En | MEDLINE | ID: mdl-34071840