Adaptive adversarial neural networks for the analysis of lossy and domain-shifted datasets of medical images.
Nat Biomed Eng
; 5(6): 571-585, 2021 06.
Article
in En
| MEDLINE
| ID: mdl-34112997
ABSTRACT
In machine learning for image-based medical diagnostics, supervised convolutional neural networks are typically trained with large and expertly annotated datasets obtained using high-resolution imaging systems. Moreover, the network's performance can degrade substantially when applied to a dataset with a different distribution. Here, we show that adversarial learning can be used to develop high-performing networks trained on unannotated medical images of varying image quality. Specifically, we used low-quality images acquired using inexpensive portable optical systems to train networks for the evaluation of human embryos, the quantification of human sperm morphology and the diagnosis of malarial infections in the blood, and show that the networks performed well across different data distributions. We also show that adversarial learning can be used with unlabelled data from unseen domain-shifted datasets to adapt pretrained supervised networks to new distributions, even when data from the original distribution are not available. Adaptive adversarial networks may expand the use of validated neural-network models for the evaluation of data collected from multiple imaging systems of varying quality without compromising the knowledge stored in the network.
Full text:
1
Database:
MEDLINE
Main subject:
Spermatozoa
/
Image Interpretation, Computer-Assisted
/
Neural Networks, Computer
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Malaria, Falciparum
/
Supervised Machine Learning
Limits:
Female
/
Humans
/
Male
Language:
En
Year:
2021
Type:
Article