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Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7.
Meng, Bo; Kemp, Steven A; Papa, Guido; Datir, Rawlings; Ferreira, Isabella A T M; Marelli, Sara; Harvey, William T; Lytras, Spyros; Mohamed, Ahmed; Gallo, Giulia; Thakur, Nazia; Collier, Dami A; Mlcochova, Petra; Duncan, Lidia M; Carabelli, Alessandro M; Kenyon, Julia C; Lever, Andrew M; De Marco, Anna; Saliba, Christian; Culap, Katja; Cameroni, Elisabetta; Matheson, Nicholas J; Piccoli, Luca; Corti, Davide; James, Leo C; Robertson, David L; Bailey, Dalan; Gupta, Ravindra K.
Affiliation
  • Meng B; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Kemp SA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK; Division of Infection and Immunity, University College London, London, UK.
  • Papa G; MRC - Laboratory of Molecular Biology, Cambridge, UK.
  • Datir R; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Ferreira IATM; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Marelli S; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Harvey WT; Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, UK; MRC - University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Lytras S; MRC - University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Mohamed A; Pirbright Institute, Woking, Surrey, UK.
  • Gallo G; Pirbright Institute, Woking, Surrey, UK.
  • Thakur N; Pirbright Institute, Woking, Surrey, UK.
  • Collier DA; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK; Division of Infection and Immunity, University College London, London, UK.
  • Mlcochova P; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Duncan LM; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Carabelli AM; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Kenyon JC; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • Lever AM; Department of Medicine, University of Cambridge, Cambridge, UK; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
  • De Marco A; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Saliba C; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Culap K; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Cameroni E; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Matheson NJ; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK; NHS Blood and Transplant, Cambridge, UK.
  • Piccoli L; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • Corti D; Humabs Biomed SA, a subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland.
  • James LC; MRC - Laboratory of Molecular Biology, Cambridge, UK.
  • Robertson DL; MRC - University of Glasgow Centre for Virus Research, Glasgow, UK.
  • Bailey D; Pirbright Institute, Woking, Surrey, UK. Electronic address: dalan.bailey@pirbright.ac.uk.
  • Gupta RK; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK; Department of Medicine, University of Cambridge, Cambridge, UK; Africa Health Research Institute, Durban, South Africa. Electronic address: rkg20@cam.ac.uk.
Cell Rep ; 35(13): 109292, 2021 06 29.
Article in En | MEDLINE | ID: mdl-34166617
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Full text: 1 Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Year: 2021 Type: Article
Fulltext
Print
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Full text: 1 Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Limits: Animals / Humans Language: En Year: 2021 Type: Article