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A phase transition enhances the catalytic activity of SARM1, an NAD+ glycohydrolase involved in neurodegeneration.
Loring, Heather S; Czech, Victoria L; Icso, Janneke D; O'Connor, Lauren; Parelkar, Sangram S; Byrne, Alexandra B; Thompson, Paul R.
Affiliation
  • Loring HS; Department of Biochemistry and Molecular Pharmacology, UMass Medical School, Worcester, United States.
  • Czech VL; Program in Chemical Biology, UMass Medical School, Worcester, United States.
  • Icso JD; Department of Neurobiology, UMass Medical School, Worcester, United States.
  • O'Connor L; Department of Biochemistry and Molecular Pharmacology, UMass Medical School, Worcester, United States.
  • Parelkar SS; Program in Chemical Biology, UMass Medical School, Worcester, United States.
  • Byrne AB; Department of Neurobiology, UMass Medical School, Worcester, United States.
  • Thompson PR; Department of Biochemistry and Molecular Pharmacology, UMass Medical School, Worcester, United States.
Elife ; 102021 06 29.
Article in En | MEDLINE | ID: mdl-34184985

Full text: 1 Database: MEDLINE Main subject: Caenorhabditis elegans / NAD/ Nucleosidase / Citric Acid / Caenorhabditis elegans Proteins / Receptors, G-Protein-Coupled / Phase Transition Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article

Full text: 1 Database: MEDLINE Main subject: Caenorhabditis elegans / NAD/ Nucleosidase / Citric Acid / Caenorhabditis elegans Proteins / Receptors, G-Protein-Coupled / Phase Transition Type of study: Prognostic_studies Limits: Animals Language: En Year: 2021 Type: Article