Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis.

Qin, Xiaoyan; Sun, Wenjing; Wang, Chong; Li, Mingjiang; Zhao, Xingbo; Li, Changzhong; Zhang, Hui

Qin, Xiaoyan; Sun, Wenjing; Wang, Chong; Li, Mingjiang; Zhao, Xingbo; Li, Changzhong; Zhang, Hui.

Affiliation

Qin X; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Sun W; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Wang C; Department of Surgery, Shandong Rongjun General Hospital, Jinan, Shandong, 250013, People's Republic of China.
Li M; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Zhao X; Department of Obstetrics and Gynaecology, Shandong University, Jinan, Shandong, 250000, People's Republic of China.
Li C; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China.
Zhang H; Department of Obstetrics and Gynaecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People's Republic of China. huizhang1218@126.com.

Reprod Biol Endocrinol ; 19(1): 114, 2021 Jul 21.

Article in En | MEDLINE | ID: mdl-34289871

Subject(s)

Adenomyosis/metabolism; B7 Antigens/biosynthesis; Inducible T-Cell Co-Stimulator Ligand/biosynthesis; Mifepristone/therapeutic use; Programmed Cell Death 1 Ligand 2 Protein/biosynthesis; V-Set Domain-Containing T-Cell Activation Inhibitor 1/biosynthesis; Adenomyosis/drug therapy; Adenomyosis/genetics; Adult; B7 Antigens/antagonists & inhibitors; B7 Antigens/genetics; Endometrium/drug effects; Endometrium/metabolism; Female; Gene Expression; Hormone Antagonists/pharmacology; Hormone Antagonists/therapeutic use; Humans; Immune Checkpoint Inhibitors/pharmacology; Immune Checkpoint Inhibitors/therapeutic use; Inducible T-Cell Co-Stimulator Ligand/antagonists & inhibitors; Inducible T-Cell Co-Stimulator Ligand/genetics; Middle Aged; Mifepristone/pharmacology; Programmed Cell Death 1 Ligand 2 Protein/antagonists & inhibitors; Programmed Cell Death 1 Ligand 2 Protein/genetics; V-Set Domain-Containing T-Cell Activation Inhibitor 1/antagonists & inhibitors; V-Set Domain-Containing T-Cell Activation Inhibitor 1/genetics

Key words

Adenomyosis; B7-H2; B7-H3; B7-H4; Mifepristone; PD-L2

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Full text: 1 Database: MEDLINE Main subject: Mifepristone / B7 Antigens / Inducible T-Cell Co-Stimulator Ligand / Programmed Cell Death 1 Ligand 2 Protein / V-Set Domain-Containing T-Cell Activation Inhibitor 1 / Adenomyosis Limits: Adult / Female / Humans / Middle aged Language: En Year: 2021 Type: Article

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