Genome-wide DNA (hydroxy) methylation reveals the individual epigenetic landscape importance on osteogenic phenotype acquisition in periodontal ligament cells.

Ferreira, Rogério S; Assis, Rahyza I F; Feltran, Geórgia da S; do Rosário Palma, Iasmin Caroline; Françoso, Beatriz G; Zambuzzi, Willian F; Andia, Denise C; da Silva, Rodrigo A

Ferreira, Rogério S; Assis, Rahyza I F; Feltran, Geórgia da S; do Rosário Palma, Iasmin Caroline; Françoso, Beatriz G; Zambuzzi, Willian F; Andia, Denise C; da Silva, Rodrigo A.

Affiliation

Ferreira RS; School of Dentistry, Health Science Institute, Paulista University, São Paulo, Brazil.
Assis RIF; Department of Prosthodontics and Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Feltran GDS; Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University, Botucatu, Brazil.
do Rosário Palma IC; Department of Dentistry, University of Taubaté, Taubaté, Brazil.
Françoso BG; School of Dentistry, Health Science Institute, Paulista University, São Paulo, Brazil.
Zambuzzi WF; Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University, Botucatu, Brazil.
Andia DC; School of Dentistry, Health Science Institute, Paulista University, São Paulo, Brazil.
da Silva RA; Department of Dentistry, University of Taubaté, Taubaté, Brazil.

J Periodontol ; 93(3): 435-448, 2022 03.

Article in En | MEDLINE | ID: mdl-34291826

Subject(s)

Osteogenesis; Periodontal Ligament; Cell Differentiation/genetics; Cells, Cultured; Core Binding Factor Alpha 1 Subunit/genetics; Core Binding Factor Alpha 1 Subunit/metabolism; DNA/metabolism; DNA Methylation; Epigenesis, Genetic; Methylation; Osteogenesis/genetics; Phenotype

Key words

DNA methylation; epigenomics; mesenchymal stem cells; osteogenesis; transcription

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