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Dopamine-dependent early synaptic and motor dysfunctions induced by α-synuclein in the nigrostriatal circuit.
Tozzi, Alessandro; Sciaccaluga, Miriam; Loffredo, Vittorio; Megaro, Alfredo; Ledonne, Ada; Cardinale, Antonella; Federici, Mauro; Bellingacci, Laura; Paciotti, Silvia; Ferrari, Elena; La Rocca, Antonino; Martini, Alessandro; Mercuri, Nicola B; Gardoni, Fabrizio; Picconi, Barbara; Ghiglieri, Veronica; De Leonibus, Elvira; Calabresi, Paolo.
Affiliation
  • Tozzi A; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
  • Sciaccaluga M; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
  • Loffredo V; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
  • Megaro A; Institute of Biochemistry and Cell Biology - IBBC, CNR, 00015 Monterotondo scalo, Italy.
  • Ledonne A; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
  • Cardinale A; Laboratory of Experimental Neuroscience, Santa Lucia Foundation IRCCS, 00143 Rome, Italy.
  • Federici M; Department of Experimental Neurophysiology, IRCCS San Raffaele, 00166 Rome, Italy.
  • Bellingacci L; Neurology, Department of Neuroscience, Faculty of Medicine, Università Cattolica del "Sacro Cuore", 00168 Rome, Italy.
  • Paciotti S; Laboratory of Experimental Neuroscience, Santa Lucia Foundation IRCCS, 00143 Rome, Italy.
  • Ferrari E; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
  • La Rocca A; Department of Medicine and Surgery, University of Perugia, 06132 Perugia, Italy.
  • Martini A; Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.
  • Mercuri NB; Institute of Biochemistry and Cell Biology - IBBC, CNR, 00015 Monterotondo scalo, Italy.
  • Gardoni F; Laboratory of Experimental Neuroscience, Santa Lucia Foundation IRCCS, 00143 Rome, Italy.
  • Picconi B; Laboratory of Experimental Neuroscience, Santa Lucia Foundation IRCCS, 00143 Rome, Italy.
  • Ghiglieri V; Neurology Unit, Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
  • De Leonibus E; Department of Pharmacological and Biomolecular Sciences, University of Milan, 20133 Milan, Italy.
  • Calabresi P; Department of Experimental Neurophysiology, IRCCS San Raffaele, 00166 Rome, Italy.
Brain ; 144(11): 3477-3491, 2021 12 16.
Article in En | MEDLINE | ID: mdl-34297092
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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Substantia Nigra / Synaptic Transmission / Alpha-Synuclein / Neuronal Plasticity Limits: Animals Language: En Year: 2021 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Substantia Nigra / Synaptic Transmission / Alpha-Synuclein / Neuronal Plasticity Limits: Animals Language: En Year: 2021 Type: Article