Intuitive repositioning of an anti-depressant drug in combination with tivozanib: precision medicine for breast cancer therapy.

Kumar, Naveen; Raza, Masoom; Sehrawat, Seema

Kumar, Naveen; Raza, Masoom; Sehrawat, Seema.

Affiliation

Kumar N; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi-NCR, 201314, India.
Raza M; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi-NCR, 201314, India.
Sehrawat S; Precision NeuroOncology & NeuroVascular Disease Modeling Group, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Delhi-NCR, 201314, India. seema.sehrawat@snu.edu.in.

Mol Cell Biochem ; 476(11): 4177-4189, 2021 Nov.

Article in En | MEDLINE | ID: mdl-34324118

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/pharmacology; Drug Repositioning/methods; Fluvoxamine/pharmacology; Phenylurea Compounds/pharmacology; Precision Medicine/methods; Quinolines/pharmacology; Triple Negative Breast Neoplasms/drug therapy; Antidepressive Agents, Second-Generation/pharmacology; Cell Line, Tumor; Cell Movement/drug effects; Drug Synergism; Drug Therapy, Combination; Fluvoxamine/administration & dosage; Humans; Phenylurea Compounds/administration & dosage; Quinolines/administration & dosage; Signal Transduction; Triple Negative Breast Neoplasms/metabolism; Triple Negative Breast Neoplasms/pathology

Key words

Combination therapy; Companion diagnostic; Drug repositioning; Metastasis and TNBC; Precision medicine

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Full text: 1 Database: MEDLINE Main subject: Phenylurea Compounds / Quinolines / Antineoplastic Combined Chemotherapy Protocols / Fluvoxamine / Precision Medicine / Drug Repositioning / Triple Negative Breast Neoplasms Limits: Humans Language: En Year: 2021 Type: Article

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